Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervical cancer

Integration of human papillomavirus (HPV) DNA into the human genome is considered as a key event in cervical carcinogenesis. Here, we perform comprehensive characterization of large-range virus-human integration events in 16 HPV16-positive cervical tumors using the Nanopore long-read sequencing tech...

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Detalles Bibliográficos
Autores principales: Zhou, Liyuan, Qiu, Qiongzi, Zhou, Qing, Li, Jianwei, Yu, Mengqian, Li, Kezhen, Xu, Lingling, Ke, Xiaohui, Xu, Haiming, Lu, Bingjian, Wang, Hui, Lu, Weiguo, Liu, Pengyuan, Lu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091225/
https://www.ncbi.nlm.nih.gov/pubmed/35538075
http://dx.doi.org/10.1038/s41467-022-30190-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091225/
https://www.ncbi.nlm.nih.gov/pubmed/35538075
http://dx.doi.org/10.1038/s41467-022-30190-1

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