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Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions

The family of hexokinases (HKs) catalyzes the first step of glycolysis, the ATP-dependent phosphorylation of glucose to glucose-6-phosphate. While HK1 and HK2 are ubiquitously expressed, the less well-studied HK3 is primarily expressed in hematopoietic cells and tissues and is highly upregulated dur...

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Detalles Bibliográficos
Autores principales: Seiler, Kristina, Humbert, Magali, Minder, Petra, Mashimo, Iris, Schläfli, Anna M., Krauer, Deborah, Federzoni, Elena A., Vu, Bich, Moresco, James J., Yates, John R., Sadowski, Martin C., Radpour, Ramin, Kaufmann, Thomas, Sarry, Jean-Emmanuel, Dengjel, Joern, Tschan, Mario P., Torbett, Bruce E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091226/
https://www.ncbi.nlm.nih.gov/pubmed/35538058
http://dx.doi.org/10.1038/s41419-022-04891-w