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Interactions of a paracyclophane-based conjugated oligoelectrolyte with biological membranes

A three-dimensional conjugated oligoelectrolyte (COE) bearing a [2.2]paracyclophane unit (COE2-3-pCp) was synthesized. Its biological activity was determined both in vivo and in silico within the context of membrane perturbation and biocompatibility. Molecular dynamics simulations indicate that, com...

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Detalles Bibliográficos
Autores principales: Limwongyut, Jakkarin, Liu, Yang, Chilambi, Gayatri Shankar, Seviour, Thomas, Hinks, Jamie, Mu, Yuguang, Bazan, Guillermo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091243/
https://www.ncbi.nlm.nih.gov/pubmed/35558200
http://dx.doi.org/10.1039/c8ra08069k