Cargando…
Interactions of a paracyclophane-based conjugated oligoelectrolyte with biological membranes
A three-dimensional conjugated oligoelectrolyte (COE) bearing a [2.2]paracyclophane unit (COE2-3-pCp) was synthesized. Its biological activity was determined both in vivo and in silico within the context of membrane perturbation and biocompatibility. Molecular dynamics simulations indicate that, com...
Autores principales: | Limwongyut, Jakkarin, Liu, Yang, Chilambi, Gayatri Shankar, Seviour, Thomas, Hinks, Jamie, Mu, Yuguang, Bazan, Guillermo C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091243/ https://www.ncbi.nlm.nih.gov/pubmed/35558200 http://dx.doi.org/10.1039/c8ra08069k |
Ejemplares similares
-
Molecular design of antimicrobial conjugated oligoelectrolytes with enhanced selectivity toward bacterial cells
por: Limwongyut, Jakkarin, et al.
Publicado: (2020) -
Membrane adaptation limitations in Enterococcus faecalis underlie sensitivity and the inability to develop significant resistance to conjugated oligoelectrolytes
por: Chilambi, Gayatri Shankar, et al.
Publicado: (2018) -
Amide Moieties Modulate the Antimicrobial Activities of Conjugated Oligoelectrolytes against Gram‐negative Bacteria
por: Limwongyut, Jakkarin, et al.
Publicado: (2022) -
Enterococcus faecalis Adapts to Antimicrobial Conjugated Oligoelectrolytes by Lipid Rearrangement and Differential Expression of Membrane Stress Response Genes
por: Chilambi, Gayatri Shankar, et al.
Publicado: (2020) -
Influence of molecular structure on the antimicrobial function of phenylenevinylene conjugated oligoelectrolytes
por: Yan, Hengjing, et al.
Publicado: (2016)