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Protein-induced fluorescence enhancement for a simple and universal detection of protein/small molecule interactions

We herein describe a novel and efficient method for the detection of protein/small molecule (SM) interactions, which relies on the protein-induced fluorescence enhancement (PIFE). In this method, a duplex probe is designed to position Cy3 and SM at the optimal distance to maximize the effect of PIFE...

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Detalles Bibliográficos
Autores principales: Kim, Hansol, Lee, Chang Yeol, Song, Jayeon, Yoon, Junhyeok, Park, Ki Soo, Park, Hyun Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091315/
https://www.ncbi.nlm.nih.gov/pubmed/35558217
http://dx.doi.org/10.1039/c8ra08515c