Cholesterol-sensing role of phenylalanine in the interaction of human islet amyloid polypeptide with lipid bilayers

The interactions between hIAPP and the pancreatic β-cells are associated with β-cell death in type II diabetes. Cholesterol modulates hIAPP-membrane interaction and hIAPP aggregation. The molecular mechanism underlying this is not well understood. Here we explore the cholesterol-sensing role of F15...

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Detalles Bibliográficos
Autores principales: Hao, Ruijie, Li, Yang, Guan, Liping, Lu, Tong, Meng, Feihong, Wang, Chunyu, Li, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091444/
https://www.ncbi.nlm.nih.gov/pubmed/35557876
http://dx.doi.org/10.1039/c8ra07310d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091444/
https://www.ncbi.nlm.nih.gov/pubmed/35557876
http://dx.doi.org/10.1039/c8ra07310d

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