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Selective Targeting of Serotonin 5-HT1a and 5-HT3 Receptors Attenuates Acute and Long-Term Hypersensitivity Associated With Neonatal Procedural Pain

Neonatal painful procedures causes acute pain and trigger long-term changes in nociceptive processing and anxiety behavior, highlighting the need for adequate analgesia during this critical time. Spinal serotonergic receptors 5-HT1a and 5-HT3 play an important role in modulating incoming nociceptive...

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Detalles Bibliográficos
Autores principales: de Kort, Anne R., Joosten, Elbert A., Patijn, Jacob, Tibboel, Dick, van den Hoogen, Nynke J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091564/
https://www.ncbi.nlm.nih.gov/pubmed/35571143
http://dx.doi.org/10.3389/fpain.2022.872587