Design and fabrication of r-hirudin loaded dissolving microneedle patch for minimally invasive and long-term treatment of thromboembolic disease

Cardiovascular disease is the leading cause of global mortality, with anticoagulant therapy being the main prevention and treatment strategy. Recombinant hirudin (r-hirudin) is a direct thrombin inhibitor that can potentially prevent thrombosis via subcutaneous (SC) and intravenous (IV) administrati...

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Detalles Bibliográficos
Autores principales: Wu, Mengfang, Xia, Tian, Li, Yaran, Wang, Tianfa, Yang, Shijia, Yu, Jinchao, Liang, Qiaoyan, Shen, Teng, Yu, Min, Zhao, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2022
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091604/
https://www.ncbi.nlm.nih.gov/pubmed/35582638
http://dx.doi.org/10.1016/j.ajps.2022.02.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091604/
https://www.ncbi.nlm.nih.gov/pubmed/35582638
http://dx.doi.org/10.1016/j.ajps.2022.02.005

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