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Design, synthesis and structure–activity relationships of mangostin analogs as cytotoxic agents

In order to better understand the structure–activity relationship of mangostin, a series of xanthone derivatives based on α-mangostin were designed and synthesized. All the compounds were evaluated for their cytotoxicity against a panel of five human cancer cell lines (HL-60, SMMC-7721, A-549, MCF-7...

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Detalles Bibliográficos
Autores principales: Chi, Xiao-Qian, Zi, Cheng-Ting, Li, Hong-Mei, Yang, Liu, Lv, Yong-Feng, Li, Jin-Yu, Hou, Bo, Ren, Fu-Cai, Hu, Jiang-Miao, Zhou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091619/
https://www.ncbi.nlm.nih.gov/pubmed/35559306
http://dx.doi.org/10.1039/c8ra08409b