Synthesis and anti-glioblastoma effects of artemisinin-isothiocyanate derivatives

A series of novel artemisinin (ART) derivatives containing an isothiocyanate (ITC) group were synthesized. All the compounds showed more potent anti-tumor effects than those of parent dihydroartemisinin (DHA) towards glioblastoma multiforme U87 in vitro. Among them, 5b had the strongest cytotoxic ac...

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Detalles Bibliográficos
Autores principales: Nyein, Chan Myae, Zhong, Xiaolin, Lu, Junfeng, Luo, Huijuan, Wang, Jiamin, Rapposelli, Simona, Li, Mingtao, Ou-yang, Ying, Pi, Rongbiao, He, Xixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091658/
https://www.ncbi.nlm.nih.gov/pubmed/35557894
http://dx.doi.org/10.1039/c8ra08162j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091658/
https://www.ncbi.nlm.nih.gov/pubmed/35557894
http://dx.doi.org/10.1039/c8ra08162j

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