Highly functionalized pyrrolidine analogues: stereoselective synthesis and caspase-dependent apoptotic activity

Novel spiropyrrolidine heterocyclic hybrids were synthesized for the first time in a sustainable fashion employing a 1,3-dipolar cycloaddition strategy to form a new class of azomethine ylides generated from tyrosine and acenaphthenequinone. Following their synthesis and characterization, these hete...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, Raju Suresh, Almansour, Abdulrahman I., Arumugam, Natarajan, Mohammad, Faruq, Alshahrani, Waleed Shihan, D, Kotresha, Altaf, Mohammad, Azam, Mohammad, Menéndez, J. Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091711/
https://www.ncbi.nlm.nih.gov/pubmed/35559303
http://dx.doi.org/10.1039/c8ra07985d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091711/
https://www.ncbi.nlm.nih.gov/pubmed/35559303
http://dx.doi.org/10.1039/c8ra07985d

Ejemplares similares