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Highly functionalized pyrrolidine analogues: stereoselective synthesis and caspase-dependent apoptotic activity

Novel spiropyrrolidine heterocyclic hybrids were synthesized for the first time in a sustainable fashion employing a 1,3-dipolar cycloaddition strategy to form a new class of azomethine ylides generated from tyrosine and acenaphthenequinone. Following their synthesis and characterization, these hete...

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Detalles Bibliográficos
Autores principales:	Kumar, Raju Suresh, Almansour, Abdulrahman I., Arumugam, Natarajan, Mohammad, Faruq, Alshahrani, Waleed Shihan, D, Kotresha, Altaf, Mohammad, Azam, Mohammad, Menéndez, J. Carlos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091711/ https://www.ncbi.nlm.nih.gov/pubmed/35559303 http://dx.doi.org/10.1039/c8ra07985d

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