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Development of a novel multi-functional integrated bioconjugate effectively targeting K-Ras mutant pancreatic cancer
Folate receptor (FR) overexpression occurs in a variety of cancers, including pancreatic cancer. In addition, enhanced macropinocytosis exists in K-Ras mutant pancreatic cancer. Furthermore, the occurrence of intensive desmoplasia causes a hypoxic microenvironment in pancreatic cancer. In this study...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Xi'an Jiaotong University
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091918/ https://www.ncbi.nlm.nih.gov/pubmed/35582405 http://dx.doi.org/10.1016/j.jpha.2021.07.001 |