Glucuronidation of [6]-shogaol, [8]-shogaol and [10]-shogaol by human tissues and expressed UGT enzymes: identification of UGT2B7 as the major contributor

Shogaols, mainly [6]-shogaol (6S), [8]-shogaol (8S) and [10]-shogaol (10S), the predominant and characteristic pungent phytochemicals in ginger, are responsible for most of its beneficial effects. However, poor oral bioavailability owing to extensive glucuronidation limits their application. The pre...

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Detalles Bibliográficos
Autores principales: He, Liangliang, Xu, Jinjin, Wang, Qi, Zhang, Yezi, Qin, Zifei, Yu, Yang, Qian, Zhengming, Yao, Zhihong, Yao, Xinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091938/
https://www.ncbi.nlm.nih.gov/pubmed/35559294
http://dx.doi.org/10.1039/c8ra08466a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091938/
https://www.ncbi.nlm.nih.gov/pubmed/35559294
http://dx.doi.org/10.1039/c8ra08466a

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