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Enantioselective Michael addition of malonates to α,β-unsaturated ketones catalyzed by 1,2-diphenylethanediamine

A general and highly enantioselective Michael addition of malonates to cinnamones and chalcones has been developed. The commercially available 1,2-diphenylethanediamine could be directly utilized as the organocatalyst to furnish the desired adducts in satisfactory yield (61–99%) and moderate to exce...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Ye, Ling, Shi, Zhichuan, Zhao, Zhigang, Li, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091971/
https://www.ncbi.nlm.nih.gov/pubmed/35558786
http://dx.doi.org/10.1039/c8ra07809b