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AMP‐activated protein kinase α1 phosphorylates PHD2 to maintain systemic iron homeostasis
BACKGROUND: Iron is essential for all mammalian life, and either a deficiency or excess of iron can cause diseases. AMP‐activated protein kinase (AMPK) is a critical regulator of metabolic homeostasis; however, it has not been established whether AMPK regulates iron metabolism. METHODS: Iron, hepcid...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091988/ https://www.ncbi.nlm.nih.gov/pubmed/35538889 http://dx.doi.org/10.1002/ctm2.854 |