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AMP‐activated protein kinase α1 phosphorylates PHD2 to maintain systemic iron homeostasis

BACKGROUND: Iron is essential for all mammalian life, and either a deficiency or excess of iron can cause diseases. AMP‐activated protein kinase (AMPK) is a critical regulator of metabolic homeostasis; however, it has not been established whether AMPK regulates iron metabolism. METHODS: Iron, hepcid...

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Detalles Bibliográficos
Autores principales: Wang, Cheng, Zhang, Wencheng, Xu, Wenjing, Liu, Zhaoyu, Huang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091988/
https://www.ncbi.nlm.nih.gov/pubmed/35538889
http://dx.doi.org/10.1002/ctm2.854