Cargando…

AMP‐activated protein kinase α1 phosphorylates PHD2 to maintain systemic iron homeostasis

BACKGROUND: Iron is essential for all mammalian life, and either a deficiency or excess of iron can cause diseases. AMP‐activated protein kinase (AMPK) is a critical regulator of metabolic homeostasis; however, it has not been established whether AMPK regulates iron metabolism. METHODS: Iron, hepcid...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Cheng, Zhang, Wencheng, Xu, Wenjing, Liu, Zhaoyu, Huang, Kai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091988/ https://www.ncbi.nlm.nih.gov/pubmed/35538889 http://dx.doi.org/10.1002/ctm2.854

Ejemplares similares

Protein kinase C phosphorylates AMP-activated protein kinase α1 Ser487
por: Heathcote, Helen R., et al.
Publicado: (2016)

AMP-18 Targets p21 to Maintain Epithelial Homeostasis
por: Chen, Peili, et al.
Publicado: (2015)

Differential Roles of Iron Storage Proteins in Maintaining the Iron Homeostasis in Mycobacterium tuberculosis
por: Khare, Garima, et al.
Publicado: (2017)

(S)-α-Chlorohydrin Inhibits Protein Tyrosine Phosphorylation through Blocking Cyclic AMP - Protein Kinase A Pathway in Spermatozoa
por: Zhang, Hao, et al.
Publicado: (2012)

AMP-activated protein kinase modulates tau phosphorylation and tau pathology in vivo
por: Domise, Manon, et al.
Publicado: (2016)

AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation
por: Gowans, Graeme J., et al.
Publicado: (2013)

Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer
por: Gerlits, Oksana, et al.
Publicado: (2014)

The Metabolic Consequences of Hepatic AMP-Kinase Phosphorylation in Rainbow Trout
por: Polakof, Sergio, et al.
Publicado: (2011)

Activation of Nrf2 by Lithospermic Acid Ameliorates Myocardial Ischemia and Reperfusion Injury by Promoting Phosphorylation of AMP-Activated Protein Kinase α (AMPKα)
por: Zhang, Min, et al.
Publicado: (2021)

Cold acclimation reduces hepatic protein Kinase B and AMP‐activated protein kinase phosphorylation and increases gluconeogenesis in Rats
por: Sepa‐Kishi, Diane M., et al.
Publicado: (2018)

RNA-dependent protein kinase (PKR) depletes nutrients, inducing phosphorylation of AMP-activated kinase in lung cancer
por: Guo, Chengcheng, et al.
Publicado: (2015)

Endothelial AMP-Activated Kinase α1 Phosphorylates eNOS on Thr495 and Decreases Endothelial NO Formation
por: Zippel, Nina, et al.
Publicado: (2018)

Subcellular distribution in cerebral cortex of two proteins phosphorylated by a cAMP-dependent protein kinase
Publicado: (1979)

Axokinin phosphorylation by cAMP-dependent protein kinase is sufficient for activation of sperm flagellar motility
Publicado: (1986)

Expression of Phosphorylated AMP-Activated Protein Kinase Predicts Response to Transarterial Chemoembolization in Postoperative Cases of Hepatocellular Carcinoma
por: Zheng, Long-Yi, et al.
Publicado: (2016)

Fam20c regulates the calpain proteolysis system through phosphorylating Calpasatatin to maintain cell homeostasis
por: Liu, Xinpeng, et al.
Publicado: (2023)

Oestrogen receptors interact with the α-catalytic subunit of AMP-activated protein kinase
por: Lipovka, Yulia, et al.
Publicado: (2015)

Deletion of intestinal epithelial AMP-activated protein kinase alters distal colon permeability but not glucose homeostasis
por: Olivier, Séverine, et al.
Publicado: (2021)

Vascular and Liver Homeostasis in Juvenile Mice Require Endothelial Cyclic AMP-Dependent Protein Kinase A
por: Nedvetsky, Pavel I., et al.
Publicado: (2022)

Validation of the Antidiabetic and Hypolipidemic Effects of Hawthorn by Assessment of Gluconeogenesis and Lipogenesis Related Genes and AMP-Activated Protein Kinase Phosphorylation
por: Shih, Chun-Ching, et al.
Publicado: (2013)

Downregulation of cAMP-Dependent Protein Kinase Inhibitor-b Promotes Preeclampsia by Decreasing Phosphorylated Akt
por: Liu, Chunfeng, et al.
Publicado: (2020)

The phosphorylation status of membrane-bound nucleoside diphosphate kinase in epithelia and the role of AMP
por: Treharne, Kate J., et al.
Publicado: (2009)

FGF21 does not require adipocyte AMP-activated protein kinase (AMPK) or the phosphorylation of acetyl-CoA carboxylase (ACC) to mediate improvements in whole-body glucose homeostasis
por: Mottillo, Emilio P., et al.
Publicado: (2017)

Role of Cardiac AMP-Activated Protein Kinase in a Non-pathological Setting: Evidence From Cardiomyocyte-Specific, Inducible AMP-Activated Protein Kinase α1α2-Knockout Mice
por: Tokarska-Schlattner, Malgorzata, et al.
Publicado: (2021)

AMP-Activated Protein Kinase Signalling
por: Neumann, Dietbert, et al.
Publicado: (2019)

Mogrol Derived from Siraitia grosvenorii Mogrosides Suppresses 3T3-L1 Adipocyte Differentiation by Reducing cAMP-Response Element-Binding Protein Phosphorylation and Increasing AMP-Activated Protein Kinase Phosphorylation
por: Harada, Naoki, et al.
Publicado: (2016)

Adenylyl cyclase-cyclicAMP signaling in mood disorders: Role of the crucial phosphorylating enzyme protein kinase A
por: Dwivedi, Yogesh, et al.
Publicado: (2008)

Modulation of vimentin containing intermediate filament distribution and phosphorylation in living fibroblasts by the cAMP-dependent protein kinase
Publicado: (1989)

Myeloid FBW7 deficiency disrupts redox homeostasis and aggravates dietary-induced insulin resistance
por: Wang, Cheng, et al.
Publicado: (2020)

Green tea polyphenols alter lipid metabolism in the livers of broiler chickens through increased phosphorylation of AMP-activated protein kinase
por: Huang, Jinbao, et al.
Publicado: (2017)

Deficiency of α-1-antitrypsin influences systemic iron homeostasis
por: Ghio, Andrew J, et al.
Publicado: (2013)

The role of AMP-activated protein kinase in GVHD-causing T cells
por: Ramgopal, Archana, et al.
Publicado: (2022)

Antidiabetic and Antihyperlipidemic Effects of Clitocybe nuda on Glucose Transporter 4 and AMP-Activated Protein Kinase Phosphorylation in High-Fat-Fed Mice
por: Chen, Mei-Hsing, et al.
Publicado: (2014)

Evaluation of the main regulators of systemic iron homeostasis in pyruvate kinase deficiency
por: Zaninoni, Anna, et al.
Publicado: (2023)

AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome
por: Gaetani, Massimiliano, et al.
Publicado: (2012)

Synthetic Phosphorylation of p38α Recapitulates Protein Kinase Activity
por: Chooi, K. Phin, et al.
Publicado: (2014)

The Dynamical Mechanism of Auto-Inhibition of AMP-Activated Protein Kinase
por: Peng, Cheng, et al.
Publicado: (2011)

Identification of a novel cAMP dependent protein kinase A phosphorylation site on the human cardiac calcium channel
por: Cserne Szappanos, Henrietta, et al.
Publicado: (2017)

Redox Regulation of the AMP-Activated Protein Kinase
por: Han, Yingying, et al.
Publicado: (2010)

Protective effects of AMP-activated protein kinase in the cardiovascular system
por: Xu, Qiang, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_7rve1vikltengju2m0g3qje9q5