Cargando…

Products of gut microbial Toll/interleukin-1 receptor domain NADase activities in gnotobiotic mice and Bangladeshi children with malnutrition

Perturbed gut microbiome development has been linked to childhood malnutrition. Here, we characterize bacterial Toll/interleukin-1 receptor (TIR) protein domains that metabolize nicotinamide adenine dinucleotide (NAD), a co-enzyme with far-reaching effects on human physiology. A consortium of 26 hum...

Descripción completa

Detalles Bibliográficos
Autores principales: Weagley, James S., Zaydman, Mark, Venkatesh, Siddarth, Sasaki, Yo, Damaraju, Neha, Yenkin, Alex, Buchser, William, Rodionov, Dmitry A., Osterman, Andrei, Ahmed, Tahmeed, Barratt, Michael J., DiAntonio, Aaron, Milbrandt, Jeffrey, Gordon, Jeffrey I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092222/
https://www.ncbi.nlm.nih.gov/pubmed/35476981
http://dx.doi.org/10.1016/j.celrep.2022.110738