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A copper(ii)-catalyzed annulative formylation of o-alkynylanilines with DMF: a single-step strategy for 3-formyl indoles

In this paper, a copper(ii)-catalyzed reaction of o-alkynylanilines with dimethylformamide (DMF) in the presence of oxygen has been developed for synthesizing multisubstituted 3-formyl indole scaffolds. This one-pot reaction proceeds through a cascade 5-endo-dig cyclization followed by formylation t...

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Detalles Bibliográficos
Autores principales: Ganesan, Balaji, Senadi, Gopal Chandru, Guo, Bing-Chun, Hung, Min-Yuan, Lin, Wei-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092273/
https://www.ncbi.nlm.nih.gov/pubmed/35557929
http://dx.doi.org/10.1039/c8ra09214a