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Biocompatibility and Physiological Thiolytic Degradability of Radically Made Thioester-Functional Copolymers: Opportunities for Drug Release

[Image: see text] Being nondegradable, vinyl polymers have limited biomedical applicability. Unfortunately, backbone esters incorporated through conventional radical ring-opening methods do not undergo appreciable abiotic hydrolysis under physiologically relevant conditions. Here, PEG acrylate and d...

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Detalles Bibliográficos
Autores principales: Bingham, Nathaniel M., Nisa, Qamar un, Gupta, Priyanka, Young, Neil P., Velliou, Eirini, Roth, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092349/
https://www.ncbi.nlm.nih.gov/pubmed/35472265
http://dx.doi.org/10.1021/acs.biomac.2c00039