Env-independent protection of intrarectal SIV challenge by vaccine induction of Gag/Vif-specific CD8(+) T cells but not CD4(+) T cells

Effective T cell induction is an important strategy in HIV-vaccine development. However, it has been indicated that vaccine-induced HIV-specific CD4(+) T cells, the preferential targets of HIV infection, might increase viral acquisition after HIV exposure. We have recently developed an immunogen (Ca...

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Detalles Bibliográficos
Autores principales: Ishii, Hiroshi, Terahara, Kazutaka, Nomura, Takushi, Okazaki, Midori, Yamamoto, Hiroyuki, Shu, Tsugumine, Sakawaki, Hiromi, Miura, Tomoyuki, Watkins, David I., Matano, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092394/
https://www.ncbi.nlm.nih.gov/pubmed/35231604
http://dx.doi.org/10.1016/j.ymthe.2022.02.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092394/
https://www.ncbi.nlm.nih.gov/pubmed/35231604
http://dx.doi.org/10.1016/j.ymthe.2022.02.023

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