Single-cell immune profiling reveals a developmentally distinct CD4(+) GM-CSF(+) T-cell lineage that induces GI tract GVHD

Gastrointestinal (GI) tract involvement is a major determinant for subsequent morbidity and mortality arising during graft-versus-host disease (GVHD). CD4(+) T cells that produce granulocyte-macrophage colony stimulating factor (GM-CSF) have emerged as central mediators of inflammation in this tissu...

Descripción completa

Detalles Bibliográficos
Autores principales: Piper, Clint, Hainstock, Emma, Yin-Yuan, Cheng, Chen, Yao, Khatun, Achia, Kasmani, Moujtaba Y., Evans, John, Miller, James A., Gorski, Jack, Cui, Weiguo, Drobyski, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092418/
https://www.ncbi.nlm.nih.gov/pubmed/35015822
http://dx.doi.org/10.1182/bloodadvances.2021006084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092418/
https://www.ncbi.nlm.nih.gov/pubmed/35015822
http://dx.doi.org/10.1182/bloodadvances.2021006084

Ejemplares similares