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A prodrug strategy for the in vivo imaging of aldehyde dehydrogenase activity

Therapy resistance is one of the biggest challenges facing clinical oncology. Despite a revolution in new anti-cancer drugs targeting multiple components of the tumour microenvironment, acquired or innate resistance frequently blunts the efficacy of these treatments. Non-invasive identification of d...

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Detalles Bibliográficos
Autores principales: Pereira, Raul, Flaherty, Renée L., Edwards, Richard S., Greenwood, Hannah E., Shuhendler, Adam J., Witney, Timothy H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092432/
https://www.ncbi.nlm.nih.gov/pubmed/35656483
http://dx.doi.org/10.1039/d2cb00040g