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Understanding p300-transcription factor interactions using sequence variation and hybridization

The hypoxic response is central to cell function and plays a significant role in the growth and survival of solid tumours. HIF-1 regulates the hypoxic response by activating over 100 genes responsible for adaptation to hypoxia, making it a potential target for anticancer drug discovery. Although the...

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Detalles Bibliográficos
Autores principales: Hóbor, Fruzsina, Hegedüs, Zsófia, Ibarra, Amaurys Avila, Petrovicz, Vencel L., Bartlett, Gail J., Sessions, Richard B., Wilson, Andrew J., Edwards, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092470/
https://www.ncbi.nlm.nih.gov/pubmed/35656479
http://dx.doi.org/10.1039/d2cb00026a