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G-Protein Coupled Receptor Signaling and Mammalian Target of Rapamycin Complex 1 Regulation

The mammalian target of rapamycin (mTOR) senses upstream stimuli to regulate numerous cellular functions such as metabolism, growth, and autophagy. Increased activation of mTOR complex 1 (mTORC1) is typically observed in human disease and continues to be an important therapeutic target. Understandin...

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Detalles Bibliográficos
Autores principales: Melick, Chase H., Lama-Sherpa, Tshering D., Curukovic, Adna, Jewell, Jenna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092479/
https://www.ncbi.nlm.nih.gov/pubmed/34965982
http://dx.doi.org/10.1124/molpharm.121.000302