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G-Protein Coupled Receptor Signaling and Mammalian Target of Rapamycin Complex 1 Regulation
The mammalian target of rapamycin (mTOR) senses upstream stimuli to regulate numerous cellular functions such as metabolism, growth, and autophagy. Increased activation of mTOR complex 1 (mTORC1) is typically observed in human disease and continues to be an important therapeutic target. Understandin...
Autores principales: | Melick, Chase H., Lama-Sherpa, Tshering D., Curukovic, Adna, Jewell, Jenna L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092479/ https://www.ncbi.nlm.nih.gov/pubmed/34965982 http://dx.doi.org/10.1124/molpharm.121.000302 |
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