The Double-Edged Sword of SIRT3 in Cancer and Its Therapeutic Applications

Reprogramming of cellular energy metabolism is considered an emerging feature of cancer. Mitochondrial metabolism plays a crucial role in cancer cell proliferation, survival, and metastasis. As a major mitochondrial NAD(+)-dependent deacetylase, sirtuin3 (SIRT3) deacetylates and regulates the enzyme...

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Detalles Bibliográficos
Autores principales: Ouyang, Shumin, Zhang, Qiyi, Lou, Linlin, Zhu, Kai, Li, Zeyu, Liu, Peiqing, Zhang, Xiaolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092499/
https://www.ncbi.nlm.nih.gov/pubmed/35571098
http://dx.doi.org/10.3389/fphar.2022.871560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092499/
https://www.ncbi.nlm.nih.gov/pubmed/35571098
http://dx.doi.org/10.3389/fphar.2022.871560

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