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The Double-Edged Sword of SIRT3 in Cancer and Its Therapeutic Applications
Reprogramming of cellular energy metabolism is considered an emerging feature of cancer. Mitochondrial metabolism plays a crucial role in cancer cell proliferation, survival, and metastasis. As a major mitochondrial NAD(+)-dependent deacetylase, sirtuin3 (SIRT3) deacetylates and regulates the enzyme...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092499/ https://www.ncbi.nlm.nih.gov/pubmed/35571098 http://dx.doi.org/10.3389/fphar.2022.871560 |