Whole-genome sequencing and mutational analysis of human cord-blood derived stem and progenitor cells

Mutational signatures have been identified in cancer genomes, providing information about the causes of cancer and treatment vulnerabilities. This protocol describes an assay to determine the genotoxic mechanisms underlying these signatures using cord-blood derived hematopoietic stem and progenitor...

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Detalles Bibliográficos
Autores principales: Rosendahl Huber, Axel, van Leeuwen, Anaïs J.C. N., Peci, Flavia, de Kanter, Jurrian K., Bertrums, Eline J.M., van Boxtel, Ruben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092504/
https://www.ncbi.nlm.nih.gov/pubmed/35573477
http://dx.doi.org/10.1016/j.xpro.2022.101361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092504/
https://www.ncbi.nlm.nih.gov/pubmed/35573477
http://dx.doi.org/10.1016/j.xpro.2022.101361

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