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Imaging Mass Spectrometry Reveals Alterations in N-Linked Glycosylation That Are Associated With Histopathological Changes in Nonalcoholic Steatohepatitis in Mouse and Human

Nonalcoholic steatohepatitis (NASH) is the progressive form of nonalcoholic fatty liver disease (NAFLD) and is characterized by inflammation, hepatocyte injury, and fibrosis. Further, NASH is a risk factor for cirrhosis and hepatocellular carcinoma. Previous research demonstrated that serum N-glycan...

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Detalles Bibliográficos
Autores principales: Ochoa-Rios, Shaaron, O'Connor, Ian P., Kent, Lindsey N., Clouse, Julian M., Hadjiyannis, Yannis, Koivisto, Christopher, Pecot, Thierry, Angel, Peggi M., Drake, Richard R., Leone, Gustavo, Mehta, Anand S., Rockey, Don C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092512/
https://www.ncbi.nlm.nih.gov/pubmed/35331917
http://dx.doi.org/10.1016/j.mcpro.2022.100225