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Cytogenetically cryptic PML::RARA fusion in acute promyelocytic leukemia: Testing strategies in the modern era

Acute promyelocytic leukemia (APL) is a unique leukemia that is characterized by the PML::RARA fusion. This fusion is often detected by conventional karyotype and fluorescence in situ hybridization (FISH); however, rare cases are cryptic and require molecular techniques to identify the PML::RARA fus...

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Detalles Bibliográficos
Autores principales: Karlin, Kirill, Bryke, Christine, Dias, Ajoy, Michaels, Phillip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092513/
https://www.ncbi.nlm.nih.gov/pubmed/35572917
http://dx.doi.org/10.1016/j.lrr.2022.100320