TBHP-mediated oxidative synthesis of substituted pyrimido[4,5-d]pyrimidines from N-uracil amidines and methylarenes under metal free conditions

An efficient and operationally simple protocol has been demonstrated for the synthesis of 1,3,5,7-tetrasubstituted pyrimido[4,5-d]pyrimidines via TBHP-mediated direct oxidative coupling of N-uracil amidines and methylarenes under metal-free conditions. Due to the inherent stability of methylarenes c...

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Detalles Bibliográficos
Autor principal: Debnath, Pradip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092612/
https://www.ncbi.nlm.nih.gov/pubmed/35559119
http://dx.doi.org/10.1039/c9ra06625j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092612/
https://www.ncbi.nlm.nih.gov/pubmed/35559119
http://dx.doi.org/10.1039/c9ra06625j

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