Oncogenic RABL6A promotes NF1-associated MPNST progression in vivo

BACKGROUND: Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas with complex molecular and genetic alterations. Powerful tumor suppressors CDKN2A and TP53 are commonly disrupted along with NF1, a gene that encodes a negative regulator of Ras. Many additional factors have been i...

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Detalles Bibliográficos
Autores principales: Kohlmeyer, Jordan L, Kaemmer, Courtney A, Lingo, Joshua J, Voigt, Ellen, Leidinger, Mariah R, McGivney, Gavin R, Scherer, Amanda, Koppenhafer, Stacia L, Gordon, David J, Breheny, Patrick, Meyerholz, David K, Tanas, Munir R, Dodd, Rebecca D, Quelle, Dawn E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092646/
https://www.ncbi.nlm.nih.gov/pubmed/35571990
http://dx.doi.org/10.1093/noajnl/vdac047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092646/
https://www.ncbi.nlm.nih.gov/pubmed/35571990
http://dx.doi.org/10.1093/noajnl/vdac047

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