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UCHL1 acts as a potential oncogene and affects sensitivity of common anti-tumor drugs in lung adenocarcinoma

BACKGROUND: Lung adenocarcinoma is the leading cause of cancer death worldwide. Recently, ubiquitin C-terminal hydrolase L1 (UCHL1) has been demonstrated to be highly expressed in many tumors and plays the role of an oncogene. However, the functional mechanism of UCHL1 is unclear in lung adenocarcin...

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Detalles Bibliográficos
Autores principales: Yao, Jianbo, Reyimu, Abdusemer, Sun, Ao, Duoji, Zaxi, Zhou, Wubi, Liang, Song, Hu, Suxia, Wang, Xiang, Dai, Jingjing, Xu, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092673/
https://www.ncbi.nlm.nih.gov/pubmed/35546675
http://dx.doi.org/10.1186/s12957-022-02620-3