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Prioritization of risk genes in multiple sclerosis by a refined Bayesian framework followed by tissue-specificity and cell type feature assessment

BACKGROUND: Multiple sclerosis (MS) is a debilitating immune-mediated disease of the central nervous system that affects over 2 million people worldwide, resulting in a heavy burden to families and entire communities. Understanding the genetic basis underlying MS could help decipher the pathogenesis...

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Detalles Bibliográficos
Autores principales: Liu, Andi, Manuel, Astrid M., Dai, Yulin, Zhao, Zhongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092676/
https://www.ncbi.nlm.nih.gov/pubmed/35545758
http://dx.doi.org/10.1186/s12864-022-08580-y