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Melanoma cells with diverse invasive potential differentially induce the activation of normal human fibroblasts

BACKGROUND: The tumor microenvironment consists of stromal cells, extracellular matrix, and physicochemical properties (e.g., oxygenation, acidification). An important element of the tumor niche are cancer-associated fibroblasts (CAFs). They may constitute up to 80% of the tumor mass and share some...

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Detalles Bibliográficos
Autores principales: Mazurkiewicz, Justyna, Simiczyjew, Aleksandra, Dratkiewicz, Ewelina, Pietraszek-Gremplewicz, Katarzyna, Majkowski, Michał, Kot, Magdalena, Ziętek, Marcin, Matkowski, Rafał, Nowak, Dorota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092709/
https://www.ncbi.nlm.nih.gov/pubmed/35538545
http://dx.doi.org/10.1186/s12964-022-00871-x