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miR-23b-3p rescues cognition in Alzheimer’s disease by reducing tau phosphorylation and apoptosis via GSK-3β signaling pathways

Dysregulated microRNA (miRNA) expression in the brain can contribute to cognitive dysfunction and aberrant tau hyperphosphorylation in Alzheimer’s disease (AD). Several studies have reported a role for microRNA-23b-3p (miR-23b-3p) in various neurologic disorders; however, its involvement in cognitio...

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Detalles Bibliográficos
Autores principales: Jiang, Hailun, Liu, Jianghong, Guo, Shuilong, Zeng, Li, Cai, Zhongdi, Zhang, Junxia, Wang, Linlin, Li, Zhuorong, Liu, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092887/
https://www.ncbi.nlm.nih.gov/pubmed/35592504
http://dx.doi.org/10.1016/j.omtn.2022.04.008