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Proximity ligation assay to detect DUX4 protein in FSHD1 muscle: a pilot study
OBJECTIVE: Aberrant expression in skeletal muscle of DUX4, a double homeobox transcription factor, underlies pathogenesis in facioscapulohumeral muscular dystrophy (FSHD). Although previous studies of FSHD muscle biopsies detected mRNAs encoding DUX4 and its target genes, no studies had reported det...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092897/ https://www.ncbi.nlm.nih.gov/pubmed/35538497 http://dx.doi.org/10.1186/s13104-022-06054-8 |