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Proximity ligation assay to detect DUX4 protein in FSHD1 muscle: a pilot study

OBJECTIVE: Aberrant expression in skeletal muscle of DUX4, a double homeobox transcription factor, underlies pathogenesis in facioscapulohumeral muscular dystrophy (FSHD). Although previous studies of FSHD muscle biopsies detected mRNAs encoding DUX4 and its target genes, no studies had reported det...

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Detalles Bibliográficos
Autores principales:	Beermann, Mary Lou, Homma, Sachiko, Miller, Jeffrey Boone
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Note
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092897/ https://www.ncbi.nlm.nih.gov/pubmed/35538497 http://dx.doi.org/10.1186/s13104-022-06054-8

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