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The A137R Protein of African Swine Fever Virus Inhibits Type I Interferon Production via the Autophagy-Mediated Lysosomal Degradation of TBK1

African swine fever is a lethal hemorrhagic disease of pigs caused by African swine fever virus (ASFV), which greatly threatens the pig industry in many countries. Deletion of virulence-associated genes to develop live attenuated ASF vaccines is considered to be a promising strategy. A recent study...

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Detalles Bibliográficos
Autores principales: Sun, Maowen, Yu, Shaoxiong, Ge, Hailiang, Wang, Tao, Li, Yongfeng, Zhou, Pingping, Pan, Li, Han, Yu, Yang, Yuying, Sun, Yuan, Li, Su, Li, Lian-Feng, Qiu, Hua-Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093111/
https://www.ncbi.nlm.nih.gov/pubmed/35412346
http://dx.doi.org/10.1128/jvi.01957-21