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A dynamic DNA nanosponge for triggered amplification of gene-photodynamic modulation

Nucleic acid therapeutics has reached clinical utility through modulating gene expression. As a potential oligonucleotide drug, DNAzyme has RNA-cleaving activity for gene silencing, but faces challenges due to the lack of a safe and effective delivery vehicle and low in vivo catalytic activity. Here...

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Detalles Bibliográficos
Autores principales: Luo, Dan, Lin, Xue, Zhao, Yun, Hu, Jialing, Mo, Fengye, Song, Gege, Zou, Zhiqiao, Wang, Fuan, Liu, Xiaoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093187/
https://www.ncbi.nlm.nih.gov/pubmed/35655573
http://dx.doi.org/10.1039/d2sc00459c