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Single-component nanodiscs via the thermal folding of amphiphilic graft copolymers with the adjusted flexibility of the main chain

Nanodiscs have attracted considerable attention as structural scaffolds for membrane-protein research and as biomaterials in e.g. drug-delivery systems. However, conventional disc-fabrication methods are usually laborious, and disc fabrication via the self-assembly of amphiphiles is difficult. Herei...

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Detalles Bibliográficos
Autores principales: Nishimura, Tomoki, Hatatani, Yusuke, Ando, Mitsuru, Sasaki, Yoshihiro, Akiyoshi, Kazunari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093194/
https://www.ncbi.nlm.nih.gov/pubmed/35655565
http://dx.doi.org/10.1039/d2sc01674e