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Campylobacter jejuni Cytolethal Distending Toxin Induces GSDME-Dependent Pyroptosis in Colonic Epithelial Cells

BACKGROUND: Cytolethal distending toxin (CDT) is a critical virulence factor of Campylobacter jejuni, and it induces cell death and regulates inflammation response in human epithelial cells. Pyroptosis is an inflammatory form of programmed cell death (PCD), but whether it is involved in CDT-mediated...

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Detalles Bibliográficos
Autores principales: Gu, Jiayun, Lin, Yan, Wang, Zhichao, Pan, Qicong, Cai, Guohua, He, Qigai, Xu, Xiaojuan, Cai, Xuwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093597/
https://www.ncbi.nlm.nih.gov/pubmed/35573789
http://dx.doi.org/10.3389/fcimb.2022.853204