Epithelia-Sensory Neuron Cross Talk Underlies Cholestatic Itch Induced by Lysophosphatidylcholine

BACKGROUND & AIMS: Limited understanding of pruritus mechanisms in cholestatic liver diseases hinders development of antipruritic treatments. Previous studies implicated lysophosphatidic acid (LPA) as a potential mediator of cholestatic pruritus. METHODS: Pruritogenicity of lysophosphatidylcholi...

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Detalles Bibliográficos
Autores principales: Chen, Yong, Wang, Zi-Long, Yeo, Michele, Zhang, Qiao-Juan, López-Romero, Ana E., Ding, Hui-Ping, Zhang, Xin, Zeng, Qian, Morales-Lázaro, Sara L., Moore, Carlene, Jin, Ying-Ai, Yang, Huang-He, Morstein, Johannes, Bortsov, Andrey, Krawczyk, Marcin, Lammert, Frank, Abdelmalek, Manal, Diehl, Anna Mae, Milkiewicz, Piotr, Kremer, Andreas E., Zhang, Jennifer Y., Nackley, Andrea, Reeves, Tony E., Ko, Mei-Chuan, Ji, Ru-Rong, Rosenbaum, Tamara, Liedtke, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093619/
https://www.ncbi.nlm.nih.gov/pubmed/33819485
http://dx.doi.org/10.1053/j.gastro.2021.03.049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093619/
https://www.ncbi.nlm.nih.gov/pubmed/33819485
http://dx.doi.org/10.1053/j.gastro.2021.03.049

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