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An Antibiotic-Loaded Hydrogel Demonstrates Efficacy as Prophylaxis and Treatment in a Large Animal Model of Orthopaedic Device-Related Infection

Local antibiotic therapy is increasingly being recognised for its role in preventing and treating orthopaedic device-related infection (ODRI). A bioresorbable, injectable gentamicin-loaded hydrogel has been developed to deliver local antibiotics at the time of surgery with potential for both prevent...

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Detalles Bibliográficos
Autores principales: Boot, Willemijn, Foster, Andrew Lewis, Guillaume, Olivier, Eglin, David, Schmid, Tanja, D’Este, Matteo, Zeiter, Stephan, Richards, Robert Geoff, Moriarty, Thomas Fintan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093643/
https://www.ncbi.nlm.nih.gov/pubmed/35573772
http://dx.doi.org/10.3389/fcimb.2022.826392