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The Host CYP1A1-Microbiota Metabolic Axis Promotes Gut Barrier Disruption in Methicillin-Resistant Staphylococcus aureus-Induced Abdominal Sepsis

BACKGROUND: Host-microbiota crosstalk has been implicated in multiple host metabolic pathway axes that regulate intestinal barrier function. Although constitutive cytochrome P4501A1 (CYP1A1) expression perturbs the microbiome-derived autoregulatory loop following enteric infection, little is known a...

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Detalles Bibliográficos
Autores principales: Ma, Xiaoyuan, Jin, Huaijian, Chu, Xiang, Dai, Weihong, Tang, Wanqi, Zhu, Junyu, Wang, Fangjie, Yang, Xue, Li, Wei, Liu, Guodong, Yang, Xia, Liang, Huaping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093654/
https://www.ncbi.nlm.nih.gov/pubmed/35572636
http://dx.doi.org/10.3389/fmicb.2022.802409