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H(2)O(2) down-regulates SIRT7’s protective role of endothelial premature dysfunction via microRNA-335-5p

Endothelial senescence is believed to constitute the initial pathogenesis of the atherosclerotic cardiovascular disease (ASCVD). MicroRNA-335-5p (miR-335-5p) expression is significantly up-regulated in oxidative stress-induced endothelial cells (ECs). Sirtuin7 (SIRT7) is considered to prevent EC sen...

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Detalles Bibliográficos
Autores principales: Liu, Yixin, Yang, Jinyu, Yang, Xi, Lai, Peng, Mou, Yi, Deng, Juelin, Li, Xinyi, Wang, Hui, Liu, Xiaolei, Zhou, Lixing, Deng, Linghui, Xu, Ziqi, Xiao, Chun, Dong, Birong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093694/
https://www.ncbi.nlm.nih.gov/pubmed/34981113
http://dx.doi.org/10.1042/BSR20211775