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Inactivation of Prefrontal Cortex Attenuates Behavioral Arousal Induced by Stimulation of Basal Forebrain During Sevoflurane Anesthesia

Cholinergic stimulation of prefrontal cortex (PFC) can reverse anesthesia. Conversely, inactivation of PFC can delay emergence from anesthesia. PFC receives cholinergic projections from basal forebrain, which contains wake-promoting neurons. However, the role of basal forebrain cholinergic neurons i...

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Detalles Bibliográficos
Autores principales: Dean, Jon G., Fields, Christopher W., Brito, Michael A., Silverstein, Brian H., Rybicki-Kler, Chloe, Fryzel, Anna M., Groenhout, Trent, Liu, Tiecheng, Mashour, George A., Pal, Dinesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkin 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093733/
https://www.ncbi.nlm.nih.gov/pubmed/35436248
http://dx.doi.org/10.1213/ANE.0000000000006011