Cargando…

DNA Damage, Defective DNA Repair, and Neurodegeneration in Amyotrophic Lateral Sclerosis

DNA is under constant attack from both endogenous and exogenous sources, and when damaged, specific cellular signalling pathways respond, collectively termed the “DNA damage response.” Efficient DNA repair processes are essential for cellular viability, although they decline significantly during agi...

Descripción completa

Detalles Bibliográficos
Autores principales: Konopka, Anna, Atkin, Julie D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093740/
https://www.ncbi.nlm.nih.gov/pubmed/35572138
http://dx.doi.org/10.3389/fnagi.2022.786420