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Hypoxia induces adrenomedullin from lung epithelia, stimulating ILC2 inflammation and immunity
Hypoxia contributes to airway inflammation and remodeling in several lung diseases; however, exactly how hypoxic pulmonary epithelium regulates allergic inflammation remains to be fully characterized. Here, we report that conditional deletion of the E3 ubiquitin ligase VHL in lung epithelial cells r...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093746/ https://www.ncbi.nlm.nih.gov/pubmed/35532553 http://dx.doi.org/10.1084/jem.20211985 |